2. Signaling Pathways
  3. Anti-infection
  4. Parasite

Parasite

Parasite

Related Products

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Antiparasitics are a class of medications which are indicated for the treatment of parasitic diseases such as nematodes, cestodes, trematodes, and infectious protozoa.

Parasite Isoform Specific Products:

Parasite Isoform Comparison
Cat. No. Product Name Effect Purity Chemical Structure
  • HY-B1099R
    Hycanthone (Standard)
    		Inhibitor
    Hycanthone (Standard) is the analytical standard of Hycanthone. This product is intended for research and analytical applications. Hycanthone is a thioxanthenone DNA intercalator and inhibits RNA synthesis as well as the DNA topoisomerases I and II. Hycanthone inhibits nucleic acid biosynthesis and inhibits apurinic endonuclease-1 (APE1) by direct protein binding with a KD of 10 nM. Hycanthone is a bioactive metabolite of Lucanthone (HY-B2098) and has anti-schistosomal agent.
    Hycanthone (Standard)
  • HY-W079315
    5-Phenylthieno[2,3-d]pyrimidin-4-amine
    5-Phenylthieno[2,3-d]pyrimidin-4-amine (Compound 3b) is a heterocyclic compound with antiviral and antiprotozoal activities.
    5-Phenylthieno[2,3-d]pyrimidin-4-amine
  • HY-155401
    Antitrypanosomal agent 18
    		Inhibitor
    Antitrypanosomal agent 18 (compound 8b) is a nitrofuran derivative has strong trypanocidal activity in vitro with an IC50 value of 0.03 μM.
    Antitrypanosomal agent 18
  • HY-N12232
    Carbazomycin D
    		Inhibitor
    Carbazomycin D exhibits antituberculosis and antimalarial activities, that inhibits Plasmodium falciparum with an IC50 > 10 μg/mL, inhibits Mycobacterium tuberculosis with MIC of 25 μg/mL. Carbazomycin D exhibits cytotoxicity in cell MCF-7, KB, NCI-H187 and Vero, with IC50s of 21.3, 33.2, 12.9, and 34.3 μg/mL, respectively.
    Carbazomycin D
  • HY-175506
    RyRs activator 6
    		Inhibitor
    RyRs activator 6 (compound C3) is a ryanodine receptor (RyRs) activator that activates calcium release in insect neurons. RyRs activator 6 has insecticidal activity.
    RyRs activator 6
  • HY-163780
    AChE-IN-66
    		Inhibitor
    Nematicidal agent 1 is a potent nematicidal agent. Nematicidal agent 1 binds to the pocket of acetylcholine esterase (AChE).
    AChE-IN-66
  • HY-N0336R
    3-Butylidenephthalide (Standard)
    		Inhibitor
    3-Butylidenephthalide (Standard) is the analytical standard of 3-Butylidenephthalide. This product is intended for research and analytical applications. 3-Butylidenephthalide (Butylidenephthalide) is a phthalic anhydride derivative identified in Ligusticum chuanxiong Hort, and has larvicidal activity (LC50 of 1.56 mg/g for Spodoptera litura larvae).
    3-Butylidenephthalide (Standard)
  • HY-13832R
    Atovaquone (Standard)
    		Inhibitor
    Atovaquone (Standard) is the analytical standard of Atovaquone. This product is intended for research and analytical applications. Atovaquone (Atavaquone) is a potent, selective and orally active inhibitor of the parasite’s mitochondrial cytochrome bc1 complex. Atovaquone is against human and  P. falciparum cytochrome bc1 activity with IC50 values of 460 nM and 2.0 nM, respectively. Atovaquone is an antimalarial agent and has the potential for the investigation of neumocystis pneumonia, toxoplasmosis, malaria, and babesia.
    Atovaquone (Standard)
  • HY-179710
    SET-12
    		Inhibitor
    SET-12 is an antiparasitic agent with high activity and selectivity against the Leishmania amazonensis. SET-12 exhibits excellent activity against the pre-flagellated form of the Leishmania amazonensis, with an IC₅₀ of 10.89 μM and a selectivity index (SI) of up to 12.1. SET-12 is also effective against the non-flagellated form within cells, with an IC₅₀ of 3.81 μM and a further increased selectivity index (SI) to 34.5. SET-12 causes signs of parasite cell apoptosis, including mitochondrial damage and accumulation of ROS.
    SET-12
  • HY-N8484
    Eprinomectin B1b
    Eprinomectin B1b is a minor component and belongs to the avermectin family of insecticides and anthelmintics.
    Eprinomectin B1b
  • HY-W018025R
    5,6-Dihydroxyindole (Standard)
    		Inhibitor
    5,6-Dihydroxyindole (Standard) is the analytical standard of 5,6-Dihydroxyindole. This product is intended for research and analytical applications. 5,6-Dihydroxyindole, a melanin precursor, has a broad-spectrum antibacterial, antifungal, antiviral, antiparasitic activity. 5,6-Dihydroxyindole has cytotoxic effects and is strongly toxic against various pathogens.
    5,6-Dihydroxyindole (Standard)
  • HY-174325
    Antimalarial agent 50
    		Inhibitor
    Antimalarial agent 50 is an antiplasmodial compound. Antimalarial agent 50 has an effect against Plasmodium berghei induced malaria infection in mice model. Antimalarial agent 50 can regulate oxidative stress and significantly reduce the levels of inflammatory factors. Antimalarial agent 50 can be used for the research of the malaria.
    Antimalarial agent 50
  • HY-N13288
    Cordysinin C/D
    		Inhibitor
    Cordysinin C/D (compound 9) is a potential anti-plasmodial compound that can effectively inhibit Plasmodium falciparum 3D7 strain.
    Cordysinin C/D
  • HY-N15187
    Acronycidine
    		Inhibitor
    Acronycidine is a quinoline alkaloid with antimalarial activity and can be extracted from Acronychia baueri Schott. Acronycidine can be utilized in malari research.
    Acronycidine
  • HY-108024AR
    Ganaplacide hydrochloride (Standard)
    		Inhibitor
    Ganaplacide hydrochloride (Standard) is the analytical standard of Ganaplacide (hydrochloride) (HY-108024A). This product is intended for research and analytical applications. Ganaplacide (KAF156) hydrochloride is a first-in-class, orally active imidazolopiperazine antimalarial agent. Ganaplacide hydrochloride is active against a broad range of Plasmodium species, including drug-resistant parasites. Ganaplacide hydrochloride is parasiticidal against both asexual and sexual blood stages as well as the liver stages of the parasite.
    Ganaplacide hydrochloride (Standard)
  • HY-180361
    Antiparasitic agent-35
    		Inhibitor
    Antiparasitic agent-35 (table 2 n = 5 R = Me) is an antiparasitic agent. Antiparasitic agent-35 shows schistosomicidal effccts.
    Antiparasitic agent-35
  • HY-W357413
    Chinifur
    		Inhibitor 98.02%
    Chinifur (Quinifuryl), a Nitrofuran derivative, is a selective inhibitor of trypanothione reductase and also a radical-generating substrate for trypanothione reductase (Ki = 4.5 μM).
    Chinifur
  • HY-168069
    DHFR-IN-20
    		Inhibitor
    DHFR-IN-20 (Compound LA1) is a Plasmodium falciparum dihydrofolate reductase (DHFR) inhibitor, with Kis of 0.16, 0.30, 6.6 nM for PfDHFR-WT, PfDHFR-QM, HsDHFR. DHFR-IN-20 has antimalarial activities (IC50: 1.4 nM and 1.6 μM for P. falciparum carrying the wild-type (TM4/8.2) and the quadruple mutant (V1/S) PfDHFR enzyme.
    DHFR-IN-20
  • HY-W727481
    Cyetpyrafen
    		Inhibitor
    Cyetpyrafen is a pyrazole insecticide/acaricide with broad-spectrum insecticidal activity. Cyetpyrafen binds to DhelOBP4 (Ki = 4.95 μM) and DhelOBP21 (Ki = 5.51 μM) to mediate olfactory recognition in *Cryptolaemus montrouzieri*. Cyetpyrafen induces dose-dependent electroantennogram responses in *Cryptolaemus montrouzieri* and exhibits repellent effects on the species. Cyetpyrafen has bioaccumulative properties, is rapidly and passively absorbed by the roots of lettuce and rice, reaches a steady state within 24 h, preferentially accumulates in roots, and shows limited xylem/phloem translocation.
    Cyetpyrafen
  • HY-N14068
    Cytosaminomycin B
    		Inhibitor
    Cytosaminomycin B has anti-Eimeria Tenella activity.
    Cytosaminomycin B
Parasite Isoform Comparison

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